Antithrombin activity of the hirudin N-terminal core domain residues 1-43
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The N-Terminal Residues 43 to 60 Form the Interface for Dopamine Mediated α-Synuclein Dimerisation
α-synuclein (α-syn) is a major component of the intracellular inclusions called Lewy bodies, which are a key pathological feature in the brains of Parkinson's disease patients. The neurotransmitter dopamine (DA) inhibits the fibrillisation of α-syn into amyloid, and promotes α-syn aggregation into SDS-stable soluble oligomers. While this inhibition of amyloid formation requires the oxidation of...
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Levvy, G. A. (1948). Biochem. J. 42, 2. Levvy, G. A. (1952). Biochem. J. 52, 464. Levvy, G. A. (1954). Biochem. J. 58, 462. Levvy, G. A. & Marsh, C. A. (1952). Biochem. J. 52, 690. Lohmar, R., Dimler, R. J., Moore, S. & Link, K. P. (1942). J. biol. Chem. 143, 551. Marsh, C. A. (1952). J. chem. Soc. p. 1578. Marsh, C. A. (1954). Biochem. J. 58, 609. Marsh, C. A., Alexander, F. & Levvy, G. A. (19...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1990
ISSN: 0014-5793
DOI: 10.1016/0014-5793(90)80105-r